The Portuguese manager had some compelling battles with Alex Ferguson’s United during his first spell with Chelsea and, having faced the Red Devils while managing both Inter Milan and Real Madrid — who ended Ferguson’s bid for a third European Cup last term — the Blues boss can’t wait for the next round.
A victory in tomorrow's match would see Chelsea go six points clear of their rivals at such an early stage and Mourinho is eager for the clash.
He said: “I lost, I won, I drew. I knocked them out of the Champions League, I was knocked out in the Champions League.
“I have everything against them.
“Maybe I won more than lost. Maybe. But playing Man United — I always say the same — gives me pleasure. I like it.
“I like the stadium, I like the opponent, I like the difficulty of the game. I like it very, very much.”
Chelsea, who confirmed today that they had reached an agreement with Anzhi Makhachkala to sign attacking midfielder Willian from under Tottenham’s noses, could be shorn of David Luiz as the Brazilian struggles with a hamstring problem.
Romelu Lukaku may be given the nod up front ahead of Fernando Torres and Demba Ba but the striker likely to receive the most attention is United’s Wayne Rooney, who has reportedly been the subject of two transfer bids by Chelsea this summer.
As a result Red Devils’ chief David Moyes will be pondering over whether or not to start the player against a club who are keen to sign him.
The Scot is without Rafael, ruled out for four weeks with a hamstring injury, while Nani (groin), Ashley Young (ankle) and Javier Hernandez (hamstring) are also not expected to feature.